A new study has found evidence that Polycystic Ovary Syndrome may begin in the brain, not the ovaries, as researchers have long speculated.

If verified, the research could change the way we think about the painful and severely misunderstood situation, which affects at least one in 10 women worldwide.

This syndrome is very difficult to diagnose due to its many different symptoms. Even if diagnosed, there are still no treatment options. Most women are simply forced to resort to the contraceptive pill solution or take other hormonal medications to manage their individual symptoms. But these do not solve the problem, they just reduce the symptoms.

In the long run, Polycystic Ovary Syndrome can lead to metabolic disorders such as type 2 diabetes, cardiovascular disease, and hormonal dysfunction, including infertility due to non-ovulation. In fact, polycystic ovary syndrome is the leading cause of all cases of non-ovulation.

And yet, despite the severity of the condition, researchers still do not understand how the syndrome develops and how we can deal with it.

Now, researchers at the University of New South Wales in Australia have shown that mice without androgen receptors (a group of steroid hormones commonly associated with men, such as testosterone) in their brains can not develop Polycystic Ovary Syndrome. But when the androgen receptors in the ovaries are removed, then the condition can arise.

Based on the similarities in the reproductive systems of mice and humans, these early indications could suggest that doctors and scientists have been focusing their efforts for a long time on treatment for the wrong organ.

The results of the research show two important things: a) that the researchers were right that excess androgens activate the condition and b) that the action of androgens in the brain is important for the development of the syndrome.

This means that if we can find a way to stop the excess of androgens in the brain, it could signal a new way of treating the syndrome.

The new study, although still early, gives researchers a new goal to consider and could lead to new, more effective treatments for women with this condition.


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